Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM164711'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164711 (US9067871, 190) Show SMILES CNC1CCc2ccc(CNS(=O)(=O)c3ccn(C)c3)cc2C1Cc1ccccc1 Show InChI InChI=1S/C24H29N3O2S/c1-25-24-11-10-20-9-8-19(16-26-30(28,29)21-12-13-27(2)17-21)15-22(20)23(24)14-18-6-4-3-5-7-18/h3-9,12-13,15,17,23-26H,10-11,14,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
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