Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50419230'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50419230 (CHEMBL1835889) Show SMILES Fc1cc(F)cc(NC(=O)CN(C2CCCCC2)C(=O)c2ccc(nc2)N2CCCC2)c1 Show InChI InChI=1S/C24H28F2N4O2/c25-18-12-19(26)14-20(13-18)28-23(31)16-30(21-6-2-1-3-7-21)24(32)17-8-9-22(27-15-17)29-10-4-5-11-29/h8-9,12-15,21H,1-7,10-11,16H2,(H,28,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GlyT1 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity binding assay				Bioorg Med Chem Lett 21: 6176-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.096 BindingDB Entry DOI: 10.7270/Q2251KF6
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