Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50138559'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50138559 (2-(7-Hydroxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-y...) Show SMILES Oc1ccc2CCN(Cc3ccccc3C(=O)NCC\C=C\c3ccccc3)CCc2c1 Show InChI InChI=1S/C28H30N2O2/c31-26-14-13-23-15-18-30(19-16-24(23)20-26)21-25-11-4-5-12-27(25)28(32)29-17-7-6-10-22-8-2-1-3-9-22/h1-6,8-14,20,31H,7,15-19,21H2,(H,29,32)/b10-6+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line				Bioorg Med Chem Lett 14: 545-8 (2003) BindingDB Entry DOI: 10.7270/Q2M9083Z
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