Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50138566'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50138566 (2-{[2-(3-Hydroxy-phenyl)-ethylamino]-methyl}-N-(4-...) Show SMILES Oc1cccc(CCNCc2ccccc2C(=O)NCCCCc2ccccc2)c1 Show InChI InChI=1S/C26H30N2O2/c29-24-14-8-12-22(19-24)16-18-27-20-23-13-4-5-15-25(23)26(30)28-17-7-6-11-21-9-2-1-3-10-21/h1-5,8-10,12-15,19,27,29H,6-7,11,16-18,20H2,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line				Bioorg Med Chem Lett 14: 545-8 (2003) BindingDB Entry DOI: 10.7270/Q2M9083Z
					More data for this Ligand-Target Pair