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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50138578'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 2


(Homo sapiens (Human))		BDBM50138578
PNG
(2-(7-Hydroxy-1-methyl-3,4-dihydro-1H-isoquinolin-2...)
Show SMILES CC1N(Cc2ccccc2C(=O)NCC\C=C\c2ccccc2)CCc2ccc(O)cc12
Show InChI InChI=1S/C28H30N2O2/c1-21-27-19-25(31)15-14-23(27)16-18-30(21)20-24-12-5-6-13-26(24)28(32)29-17-8-7-11-22-9-3-2-4-10-22/h2-7,9-15,19,21,31H,8,16-18,20H2,1H3,(H,29,32)/b11-7+
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Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line

Bioorg Med Chem Lett 14: 545-8 (2003)


BindingDB Entry DOI: 10.7270/Q2M9083Z
More data for this
Ligand-Target Pair