Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50138582'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50138582 (2-{[2-(4-Amino-phenyl)-ethylamino]-methyl}-N-(4-ph...) Show SMILES Nc1ccc(CCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1 Show InChI InChI=1S/C26H31N3O/c27-24-15-13-22(14-16-24)17-19-28-20-23-11-4-5-12-25(23)26(30)29-18-7-6-10-21-8-2-1-3-9-21/h1-5,8-9,11-16,28H,6-7,10,17-20,27H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line				Bioorg Med Chem Lett 14: 545-8 (2003) BindingDB Entry DOI: 10.7270/Q2M9083Z
					More data for this Ligand-Target Pair