Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50056578'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056578 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2ccc3ccccc3n2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H29F2N3O/c30-25-10-5-23(6-11-25)29(24-7-12-26(31)13-8-24)35-20-19-33-15-17-34(18-16-33)21-27-14-9-22-3-1-2-4-28(22)32-27/h1-14,29H,15-21H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Heights Curated by ChEMBL					Assay Description Displacement of [125I]RTI55 from DAT in rat brain synaptosomes				Bioorg Med Chem 15: 1146-59 (2006) Article DOI: 10.1016/j.bmc.2006.09.070 BindingDB Entry DOI: 10.7270/Q2M61JXC
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056578 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2ccc3ccccc3n2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H29F2N3O/c30-25-10-5-23(6-11-25)29(24-7-12-26(31)13-8-24)35-20-19-33-15-17-34(18-16-33)21-27-14-9-22-3-1-2-4-28(22)32-27/h1-14,29H,15-21H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056578 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2ccc3ccccc3n2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H29F2N3O/c30-25-10-5-23(6-11-25)29(24-7-12-26(31)13-8-24)35-20-19-33-15-17-34(18-16-33)21-27-14-9-22-3-1-2-4-28(22)32-27/h1-14,29H,15-21H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056578 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2ccc3ccccc3n2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H29F2N3O/c30-25-10-5-23(6-11-25)29(24-7-12-26(31)13-8-24)35-20-19-33-15-17-34(18-16-33)21-27-14-9-22-3-1-2-4-28(22)32-27/h1-14,29H,15-21H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-5-HT on synaptosomes obtained from whole rat brain minus cerebellum.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair