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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50250565'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM50250565
PNG
(CHEMBL4065787)
Show SMILES Cc1ccc(cc1)C([S+]([O-])Cc1cccs1)c1ccc(C)cc1
Show InChI InChI=1S/C20H20OS2/c1-15-5-9-17(10-6-15)20(18-11-7-16(2)8-12-18)23(21)14-19-4-3-13-22-19/h3-13,20H,14H2,1-2H3
NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Inhibition of re-uptake of [3H]-dopamine at human DAT expressed in HEK293 cells preincubated for 5 mins followed by [3H]-dopamine addition measured a...

J Med Chem 60: 9330-9348 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01313
BindingDB Entry DOI: 10.7270/Q26112RW
More data for this
Ligand-Target Pair