Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50369770 (CHEMBL1788140) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI. | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50369770 (CHEMBL1788140) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]DA (20 nM) by dopamine transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair |