BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50453929'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50453929
PNG
(CHEMBL4206622)
Show SMILES Cl.Cl.FCCOc1ccc(CCN2CCN(CCc3ccccc3Cl)CC2)cc1
Show InChI InChI=1S/C22H28ClFN2O/c23-22-4-2-1-3-20(22)10-13-26-16-14-25(15-17-26)12-9-19-5-7-21(8-6-19)27-18-11-24/h1-8H,9-18H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 5.36E+3n/an/an/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Inhibition of [3H]dopamine uptake at dopamine transporter in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measu...

Bioorg Med Chem Lett 27: 5467-5472 (2017)


Article DOI: 10.1016/j.bmcl.2017.10.039
BindingDB Entry DOI: 10.7270/Q2BP05B5
More data for this
Ligand-Target Pair