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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent neutral amino acid transporter B(0)AT2' and Ligand = 'BDBM50031270'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent neutral amino acid transporter B(0)AT2


(Homo sapiens (Human))		BDBM50031270
PNG
(CHEMBL3357031)
Show SMILES [#6]-[#6]-[#6]S(=O)(=O)[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12
Show InChI InChI=1S/C22H25ClN2O2S/c1-2-14-28(26,27)25-12-9-16(10-13-25)21-20-8-7-19(23)15-18(20)6-5-17-4-3-11-24-22(17)21/h3-4,7-8,11,15H,2,5-6,9-10,12-14H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



Max Planck Institute of Psychiatry

Curated by ChEMBL


Assay Description
Inhibition of eGFP-tagged human B0AT2 expressed in HEK293 cells measured within 10 mins by [3H]proline uptake assay

J Med Chem 57: 9473-9 (2014)


Article DOI: 10.1021/jm501086v
BindingDB Entry DOI: 10.7270/Q22F7Q1H
More data for this
Ligand-Target Pair