Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM202585 (US10035761, Compound 8j | US9238625, 8j) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Revivia Pharmaceuticals, Inc. US Patent | Assay Description The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ... | US Patent US10035761 (2018) BindingDB Entry DOI: 10.7270/Q2D220N9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM202585 (US10035761, Compound 8j | US9238625, 8j) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 11.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
REVIVA PHARMACEUTICALS, INC. US Patent | Assay Description The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros... | US Patent US9238625 (2016) BindingDB Entry DOI: 10.7270/Q2CV4GKK | |||||||||||
More data for this Ligand-Target Pair |