BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50172783'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50172783
PNG
(6-Chloro-3-methyl-3-(3-methylamino-propyl)-1-p-tol...)
Show SMILES CNCCCC1(C)Cc2cc(Cl)ccc2N(C1=O)c1ccc(C)cc1
Show InChI InChI=1S/C21H25ClN2O/c1-15-5-8-18(9-6-15)24-19-10-7-17(22)13-16(19)14-21(2,20(24)25)11-4-12-23-3/h5-10,13,23H,4,11-12,14H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
43n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Inhibition of monoamine reuptake at norepinephrine transporter


Bioorg Med Chem Lett 15: 4432-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.038
BindingDB Entry DOI: 10.7270/Q2G44PTW
More data for this
Ligand-Target Pair