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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM388488'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM388488
PNG
(US9944618, Compound ID No. 22)
Show SMILES CNC[C@@H]([C@H](OCc1noc(C)n1)c1ccccc1)c1ccc2ccccc2c1 |r|
Show InChI InChI=1S/C24H25N3O2/c1-17-26-23(27-29-17)16-28-24(19-9-4-3-5-10-19)22(15-25-2)21-13-12-18-8-6-7-11-20(18)14-21/h3-14,22,24-25H,15-16H2,1-2H3/t22-,24-/m1/s1
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US Patent
 2.10n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...

Bioorg Med Chem Lett 19: 1164-7 (2009)


BindingDB Entry DOI: 10.7270/Q26D5WBR
More data for this
Ligand-Target Pair