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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM388495'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM388495
PNG
(US9944618, Compound ID No. 29)
Show SMILES CCCNC(=O)CO[C@@H]([C@H](CNC)c1ccc2ccccc2c1)c1ccccc1 |r|
Show InChI InChI=1S/C25H30N2O2/c1-3-15-27-24(28)18-29-25(20-10-5-4-6-11-20)23(17-26-2)22-14-13-19-9-7-8-12-21(19)16-22/h4-14,16,23,25-26H,3,15,17-18H2,1-2H3,(H,27,28)/t23-,25-/m1/s1
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US Patent
 1.10n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...

Bioorg Med Chem Lett 19: 1164-7 (2009)


BindingDB Entry DOI: 10.7270/Q26D5WBR
More data for this
Ligand-Target Pair