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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM388521'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM388521
PNG
(US9944618, Compound ID No. 55)
Show SMILES CNC[C@@H]([C@H](O)c1cccnc1)c1ccc(OC)c(C)c1 |r|
Show InChI InChI=1S/C17H22N2O2/c1-12-9-13(6-7-16(12)21-3)15(11-18-2)17(20)14-5-4-8-19-10-14/h4-10,15,17-18,20H,11H2,1-3H3/t15-,17-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
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PC cid
PC sid
UniChem
US Patent
 1.80n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...

Bioorg Med Chem Lett 19: 1164-7 (2009)


BindingDB Entry DOI: 10.7270/Q26D5WBR
More data for this
Ligand-Target Pair