BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM388555'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM388555
PNG
(US9944618, Compound ID No. 89)
Show SMILES CN(C)C[C@@H]([C@H](OCCO)c1ccccc1)c1ccc2ccccc2c1 |r|
Show InChI InChI=1S/C23H27NO2/c1-24(2)17-22(21-13-12-18-8-6-7-11-20(18)16-21)23(26-15-14-25)19-9-4-3-5-10-19/h3-13,16,22-23,25H,14-15,17H2,1-2H3/t22-,23-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 1.80n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...

Bioorg Med Chem Lett 19: 1164-7 (2009)


BindingDB Entry DOI: 10.7270/Q26D5WBR
More data for this
Ligand-Target Pair