Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM396454'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM396454 (2-[2-(Azetidin-3-yloxy)-4-chloro-phenoxymethyl]-6-...) Show SMILES FC(F)(F)c1cccc(COc2ccc(Cl)cc2OC2CNC2)n1 Show InChI InChI=1S/C16H14ClF3N2O2/c17-10-4-5-13(14(6-10)24-12-7-21-8-12)23-9-11-2-1-3-15(22-11)16(18,19)20/h1-6,12,21H,7-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...				J Med Chem 52: 3523-38 (2009) BindingDB Entry DOI: 10.7270/Q26T0Q0F
					More data for this Ligand-Target Pair