Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50233471![]() ((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.68 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at SERT (unknown origin) | Bioorg Med Chem Lett 18: 6088-92 (2008) Article DOI: 10.1016/j.bmcl.2008.10.028 BindingDB Entry DOI: 10.7270/Q2RJ4JBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50233471![]() ((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]5HT uptake at human 5HT transporter expressed in HEK293 cells | Bioorg Med Chem Lett 18: 596-9 (2008) BindingDB Entry DOI: 10.7270/Q2DR2WBX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50233471![]() ((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells | Bioorg Med Chem Lett 18: 4018-21 (2008) Article DOI: 10.1016/j.bmcl.2008.06.001 BindingDB Entry DOI: 10.7270/Q2W37W4X | |||||||||||
More data for this Ligand-Target Pair |