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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50261039'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM50261039
PNG
(CHEMBL4101959)
Show SMILES Clc1cccc(c1)-c1nnnn1CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H26ClN5/c23-21-9-4-8-20(17-21)22-24-25-26-28(22)13-5-12-27-14-10-19(11-15-27)16-18-6-2-1-3-7-18/h1-4,6-9,17,19H,5,10-16H2
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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 1.35E+3n/an/an/an/an/an/a



College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 61186, Republic of Korea.

Curated by ChEMBL


Assay Description
Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation counting

Bioorg Med Chem 25: 5278-5289 (2017)


Article DOI: 10.1016/j.bmc.2017.07.046
BindingDB Entry DOI: 10.7270/Q28C9ZPV
More data for this
Ligand-Target Pair