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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50263919'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM50263919
PNG
(CHEMBL490382 | N-(3-((methylamino)methyl)-4-(4-(me...)
Show SMILES CSc1ccc(Oc2ccc(NS(C)(=O)=O)cc2CN(C)C)cc1F
Show InChI InChI=1S/C17H21FN2O3S2/c1-20(2)11-12-9-13(19-25(4,21)22)5-7-16(12)23-14-6-8-17(24-3)15(18)10-14/h5-10,19H,11H2,1-4H3
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells

Bioorg Med Chem Lett 18: 5303-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.040
BindingDB Entry DOI: 10.7270/Q20K28DX
More data for this
Ligand-Target Pair