Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50374598 (CHEMBL272603 | US9604926, Compound CM-156 | US9724...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | US Patent | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent | Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ... | US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50374598 (CHEMBL272603 | US9604926, Compound CM-156 | US9724...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by PDSP Ki Database | Assay Description Displacement of [3H]paroxetine from serotonin transporter in rat brain homogenate | J Med Chem 51: 1482-6 (2008) Article DOI: 10.1021/jm701357m BindingDB Entry DOI: 10.7270/Q2736RTZ | |||||||||||
More data for this Ligand-Target Pair |