BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50453921'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50453921
PNG
(CHEMBL4206313)
Show SMILES Cl.Cl.FCCOc1ccc(CCN2CCN(CCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H29FN2O/c23-12-19-26-22-8-6-21(7-9-22)11-14-25-17-15-24(16-18-25)13-10-20-4-2-1-3-5-20/h1-9H,10-19H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 3.37E+3n/an/an/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Inhibition of [3H]serotonin uptake at SERT in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measured after 10 mi...

Bioorg Med Chem Lett 27: 5467-5472 (2017)


Article DOI: 10.1016/j.bmcl.2017.10.039
BindingDB Entry DOI: 10.7270/Q2BP05B5
More data for this
Ligand-Target Pair