Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50453923'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50453923 (CHEMBL4210347) Show SMILES Cl.Cl.FCCOc1ccccc1CCN1CCN(CCc2ccc(F)cc2)CC1 Show InChI InChI=1S/C22H28F2N2O/c23-11-18-27-22-4-2-1-3-20(22)10-13-26-16-14-25(15-17-26)12-9-19-5-7-21(24)8-6-19/h1-8H,9-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]serotonin uptake at SERT in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measured after 10 mi...				Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5
					More data for this Ligand-Target Pair