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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50462916'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM50462916
PNG
(CHEMBL4243340)
Show SMILES Clc1ccc(cc1)N1CCN(CCCNC(=O)c2ccc3ccccc3c2)CC1
Show InChI InChI=1S/C24H26ClN3O/c25-22-8-10-23(11-9-22)28-16-14-27(15-17-28)13-3-12-26-24(29)21-7-6-19-4-1-2-5-20(19)18-21/h1-2,4-11,18H,3,12-17H2,(H,26,29)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 280n/an/an/an/an/an/a



Chonnam National University

Curated by ChEMBL


Assay Description
Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3H]5-HT uptake by micro beta scintillation counting analysis

Bioorg Med Chem 26: 4127-4135 (2018)


Article DOI: 10.1016/j.bmc.2018.06.043
BindingDB Entry DOI: 10.7270/Q2474DHG
More data for this
Ligand-Target Pair