Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sonic hedgehog protein' and Ligand = 'BDBM50302115'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50302115 (CHEMBL569818 | N-(4-chloro-3-(2H-indazol-2-yl)phen...) Show SMILES Cc1nc(ccc1C(=O)Nc1ccc(Cl)c(c1)-n1cc2ccccc2n1)C(F)(F)F Show InChI InChI=1S/C21H14ClF3N4O/c1-12-15(7-9-19(26-12)21(23,24)25)20(30)27-14-6-8-16(22)18(10-14)29-11-13-4-2-3-5-17(13)28-29/h2-11H,1H3,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assay				Bioorg Med Chem Lett 19: 5576-81 (2009) Article DOI: 10.1016/j.bmcl.2009.08.049 BindingDB Entry DOI: 10.7270/Q21R6QMJ
					More data for this Ligand-Target Pair