Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Sortilin' and Ligand = 'BDBM159188'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sortilin (Homo sapiens (Human))	BDBM159188 (US10195186, Example 37 | US9682967, 35) Show SMILES Cc1cc(NC(=O)c2ccc(Br)cc2C(O)=O)ncn1 Show InChI InChI=1S/C13H10BrN3O3/c1-7-4-11(16-6-15-7)17-12(18)9-3-2-8(14)5-10(9)13(19)20/h2-6H,1H3,(H,19,20)(H,15,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair
Sortilin (Homo sapiens (Human))	BDBM159188 (US10195186, Example 37 | US9682967, 35) Show SMILES Cc1cc(NC(=O)c2ccc(Br)cc2C(O)=O)ncn1 Show InChI InChI=1S/C13H10BrN3O3/c1-7-4-11(16-6-15-7)17-12(18)9-3-2-8(14)5-10(9)13(19)20/h2-6H,1H3,(H,19,20)(H,15,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.91E+3	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.4	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US9682967 (2017) BindingDB Entry DOI: 10.7270/Q22805SC
					More data for this Ligand-Target Pair
Sortilin (Homo sapiens (Human))	BDBM159188 (US10195186, Example 37 | US9682967, 35) Show SMILES Cc1cc(NC(=O)c2ccc(Br)cc2C(O)=O)ncn1 Show InChI InChI=1S/C13H10BrN3O3/c1-7-4-11(16-6-15-7)17-12(18)9-3-2-8(14)5-10(9)13(19)20/h2-6H,1H3,(H,19,20)(H,15,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair