Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Sortilin' and Ligand = 'BDBM159189'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sortilin (Homo sapiens (Human))	BDBM159189 (US10195186, Example 38 | US9682967, 36) Show SMILES COc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1 Show InChI InChI=1S/C15H11F3N2O4/c1-24-12-7-9(4-5-19-12)20-13(21)10-3-2-8(15(16,17)18)6-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	714	n/a	750	n/a	n/a	n/a	n/a	7.4	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US9682967 (2017) BindingDB Entry DOI: 10.7270/Q22805SC
					More data for this Ligand-Target Pair
Sortilin (Homo sapiens (Human))	BDBM159189 (US10195186, Example 38 | US9682967, 36) Show SMILES COc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1 Show InChI InChI=1S/C15H11F3N2O4/c1-24-12-7-9(4-5-19-12)20-13(21)10-3-2-8(15(16,17)18)6-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair
Sortilin (Homo sapiens (Human))	BDBM159189 (US10195186, Example 38 | US9682967, 36) Show SMILES COc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1 Show InChI InChI=1S/C15H11F3N2O4/c1-24-12-7-9(4-5-19-12)20-13(21)10-3-2-8(15(16,17)18)6-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...				US Patent US10195186 (2019) BindingDB Entry DOI: 10.7270/Q2474CZW
					More data for this Ligand-Target Pair