Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingomyelin phosphodiesterase 2 (Rattus norvegicus) | BDBM50128905 ((4-Dimethylamino-benzyl)-carbamic acid (E)-(2S,3R)...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme source | Bioorg Med Chem Lett 13: 1963-6 (2003) BindingDB Entry DOI: 10.7270/Q2KD1ZFT | |||||||||||
More data for this Ligand-Target Pair |