Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM192147'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM192147 (US9187437, 42 (comparative)) Show SMILES C1CCC(C(C1)c1nc(no1)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H20N2O/c1-3-9-15(10-4-1)17-13-7-8-14-18(17)20-21-19(22-23-20)16-11-5-2-6-12-16/h1-6,9-12,17-18H,7-8,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	7.5	25
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1x108 cells/pellet) were suspended in buffer containing 20 mM HEPES, pH ...				US Patent US9187437 (2015) BindingDB Entry DOI: 10.7270/Q2JH3K0X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM192147 (US9187437, 42 (comparative)) Show SMILES C1CCC(C(C1)c1nc(no1)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H20N2O/c1-3-9-15(10-4-1)17-13-7-8-14-18(17)20-21-19(22-23-20)16-11-5-2-6-12-16/h1-6,9-12,17-18H,7-8,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>6.20E+4	n/a	n/a	n/a	60
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-G...				US Patent US9187437 (2015) BindingDB Entry DOI: 10.7270/Q2JH3K0X
					More data for this Ligand-Target Pair