Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50364417'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50364417 (CHEMBL1950559) Show SMILES NCCc1ccc(-c2nc3ccc(nc3s2)C2(CC2)c2ccccc2)c(F)c1 Show InChI InChI=1S/C23H20FN3S/c24-18-14-15(10-13-25)6-7-17(18)21-26-19-8-9-20(27-22(19)28-21)23(11-12-23)16-4-2-1-3-5-16/h1-9,14H,10-13,25H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	478	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at eGFP-tagged human S1P1 receptor expressed in U2OS cells assessed as receptor internalization after 1 hr by Hoechst dye-based micr...				Bioorg Med Chem Lett 22: 1779-83 (2012) Article DOI: 10.1016/j.bmcl.2011.12.073 BindingDB Entry DOI: 10.7270/Q23R0TBJ
					More data for this Ligand-Target Pair