BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sphingosine kinase 2' and Ligand = 'BDBM50523505'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine kinase 2


(Homo sapiens (Human))		BDBM50523505
PNG
(CHEMBL4551903)
Show SMILES OC[C@H]1CCCN1Cc1ccc(COc2cccc(OCc3ccccc3F)c2)cc1 |r|
Show InChI InChI=1S/C26H28FNO3/c27-26-9-2-1-5-22(26)19-31-25-8-3-7-24(15-25)30-18-21-12-10-20(11-13-21)16-28-14-4-6-23(28)17-29/h1-3,5,7-13,15,23,29H,4,6,14,16-19H2/t23-/m1/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 55n/an/an/an/an/an/a



Heriot-Watt University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human full-length N-terminal His-tagged SK2 expressed in baculovirus infected Sf9 insect cells using Sph as substrate measu...

J Med Chem 62: 3658-3676 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00162
BindingDB Entry DOI: 10.7270/Q2QV3QZ4
More data for this
Ligand-Target Pair