Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Spindlin-1' and Ligand = 'BDBM50505571'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Spindlin-1 (Homo sapiens)	BDBM50505571 (CHEMBL4528213) Show SMILES CC1(C)C(N)=Nc2cc(OCCCN3Cc4ccccc4C3)c(OCC3CC3)cc12 |c:4| Show InChI InChI=1S/C25H31N3O2/c1-25(2)20-12-22(30-16-17-8-9-17)23(13-21(20)27-24(25)26)29-11-5-10-28-14-18-6-3-4-7-19(18)15-28/h3-4,6-7,12-13,17H,5,8-11,14-16H2,1-2H3,(H2,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...				J Med Chem 62: 9008-9025 (2019) Article DOI: 10.1021/acs.jmedchem.9b00562 BindingDB Entry DOI: 10.7270/Q27S7S2S
					More data for this Ligand-Target Pair
Spindlin-1 (Homo sapiens)	BDBM50505571 (CHEMBL4528213) Show SMILES CC1(C)C(N)=Nc2cc(OCCCN3Cc4ccccc4C3)c(OCC3CC3)cc12 |c:4| Show InChI InChI=1S/C25H31N3O2/c1-25(2)20-12-22(30-16-17-8-9-17)23(13-21(20)27-24(25)26)29-11-5-10-28-14-18-6-3-4-7-19(18)15-28/h3-4,6-7,12-13,17H,5,8-11,14-16H2,1-2H3,(H2,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Binding affinity to recombinant human His-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constan...				J Med Chem 62: 9008-9025 (2019) Article DOI: 10.1021/acs.jmedchem.9b00562 BindingDB Entry DOI: 10.7270/Q27S7S2S
					More data for this Ligand-Target Pair
Spindlin-1 (Homo sapiens)	BDBM50505571 (CHEMBL4528213) Show SMILES CC1(C)C(N)=Nc2cc(OCCCN3Cc4ccccc4C3)c(OCC3CC3)cc12 |c:4| Show InChI InChI=1S/C25H31N3O2/c1-25(2)20-12-22(30-16-17-8-9-17)23(13-21(20)27-24(25)26)29-11-5-10-28-14-18-6-3-4-7-19(18)15-28/h3-4,6-7,12-13,17H,5,8-11,14-16H2,1-2H3,(H2,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Binding affinity to human His-tagged SPIN1 (21 to 262 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant preincubat...				J Med Chem 62: 9008-9025 (2019) Article DOI: 10.1021/acs.jmedchem.9b00562 BindingDB Entry DOI: 10.7270/Q27S7S2S
					More data for this Ligand-Target Pair