Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Ligand = 'BDBM50342185'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342185 (CHEMBL1766186 | rac-N-[4'-[1-Hydroxy(1H-imidazol-4...) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)c1cnc[nH]1 Show InChI InChI=1S/C18H17N3O2/c1-12(22)21-16-4-2-3-15(9-16)13-5-7-14(8-6-13)18(23)17-10-19-11-20-17/h2-11,18,23H,1H3,(H,19,20)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342185 (CHEMBL1766186 | rac-N-[4'-[1-Hydroxy(1H-imidazol-4...) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)c1cnc[nH]1 Show InChI InChI=1S/C18H17N3O2/c1-12(22)21-16-4-2-3-15(9-16)13-5-7-14(8-6-13)18(23)17-10-19-11-20-17/h2-11,18,23H,1H3,(H,19,20)(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair