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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM383177'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Homo sapiens (Human))		BDBM383177
PNG
(US10278962, Compound 8)
Show SMILES CC(=O)OCC(C)(OC(C)=O)[C@@H]1C[C@H](OC(=O)c2ccc(cc2)C#N)[C@@]2(C)Oc3cc(oc(=O)c3[C@@H](OC(C)=O)[C@@H]2C1)-c1cccnc1 |r,w:5.4|
Show InChI InChI=1S/C35H34N2O11/c1-19(38)43-18-34(4,47-21(3)40)25-13-26-31(44-20(2)39)30-28(15-27(45-33(30)42)24-7-6-12-37-17-24)48-35(26,5)29(14-25)46-32(41)23-10-8-22(16-36)9-11-23/h6-12,15,17,25-26,29,31H,13-14,18H2,1-5H3/t25-,26-,29-,31-,34?,35-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.47E+4n/an/an/an/an/an/a



National Taiwan University



Assay Description
1. Purpose:The analogues of Pyripyropene A structure were tested for their inhibitory effect on ACAT2 activity at intact cellular level by a method i...

J Med Chem 51: 5594-607 (2008)


BindingDB Entry DOI: 10.7270/Q2CF9SF8
More data for this
Ligand-Target Pair