Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM50106693'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50106693 ((5,6-Diphenyl-pyridazin-3-yl)-octyl-amine | CHEMBL...) Show SMILES CCCCCCCCNc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C24H29N3/c1-2-3-4-5-6-13-18-25-23-19-22(20-14-9-7-10-15-20)24(27-26-23)21-16-11-8-12-17-21/h7-12,14-17,19H,2-6,13,18H2,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Acyl-coenzyme A:cholesterol acyltransferase in macrophages				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106693 ((5,6-Diphenyl-pyridazin-3-yl)-octyl-amine | CHEMBL...) Show SMILES CCCCCCCCNc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C24H29N3/c1-2-3-4-5-6-13-18-25-23-19-22(20-14-9-7-10-15-20)24(27-26-23)21-16-11-8-12-17-21/h7-12,14-17,19H,2-6,13,18H2,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
					More data for this Ligand-Target Pair