BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM50242257'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sterol O-acyltransferase 1 (Cricetulus griseus)	BDBM50242257 (2-((1R,2S,4aS)-1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Inhibition of SOAT1 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based method				Bioorg Med Chem Lett 29: 2283-2285 (2019) Article DOI: 10.1016/j.bmcl.2019.06.026 BindingDB Entry DOI: 10.7270/Q2NK3JC2
Kitasato University Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Chlorocebus aethiops)	BDBM50242257 (2-((1R,2S,4aS)-1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based method				Bioorg Med Chem Lett 29: 2283-2285 (2019) Article DOI: 10.1016/j.bmcl.2019.06.026 BindingDB Entry DOI: 10.7270/Q2NK3JC2
Kitasato University Curated by ChEMBL					More data for this Ligand-Target Pair