Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein [H232R]' and Ligand = 'BDBM490791'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stimulator of interferon genes protein [H232R] (Homo sapiens (Human))	BDBM490791 (9-((4S,6R,7S,11aR,13R,14R,14aR,15R)-13-(6-amino-9H...) Show SMILES Cn1cnc2n(cnc2c1=O)[C@@H]1C[C@@H]2OP(S)(=S)O[C@H]3[C@@H](F)[C@@H](O[C@@H]3COP(S)(=S)O[C@@H]1[C@@H]2O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C21H24FN9O7P2S4/c1-29-5-28-19-13(20(29)33)27-6-30(19)8-2-9-14(32)15(8)37-39(41,42)34-3-10-16(38-40(43,44)36-9)11(22)21(35-10)31-7-26-12-17(23)24-4-25-18(12)31/h4-11,14-16,21,32H,2-3H2,1H3,(H,41,42)(H,43,44)(H2,23,24,25)/t8-,9+,10-,11-,14-,15+,16-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...				US Patent US10968242 (2021) BindingDB Entry DOI: 10.7270/Q27W6GB9
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