Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-P receptor (Homo sapiens (Human)) | BDBM50030228 ((S)-((S)-3-Benzhydryl-octahydro-2,5-methano-isoqui...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc. Curated by ChEMBL | Assay Description Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligand | J Med Chem 37: 2831-40 (1994) BindingDB Entry DOI: 10.7270/Q2CZ365J | |||||||||||
More data for this Ligand-Target Pair |