Compile Data Set for Download or QSAR

Found 11 hits Enz. Inhib. hit(s) with Target = 'Sucrase-isomaltase, intestinal' and Ligand = 'BDBM50242271'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal brush border membrane sucrase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Kindai University Curated by ChEMBL					Assay Description Inhibition of rat small intestinal sucrase using sucrose as substrate incubated for 30 mins by glucose-oxidase method				Bioorg Med Chem 24: 3705-15 (2016) Article DOI: 10.1016/j.bmc.2016.06.013 BindingDB Entry DOI: 10.7270/Q241700V
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Homo sapiens (Human))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of sucrase by HPLC				J Med Chem 53: 689-98 (2010) Article DOI: 10.1021/jm901281m BindingDB Entry DOI: 10.7270/Q2M908TC
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal sucrase using sucrose as substrate				J Med Chem 55: 10347-62 (2012) Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 3298-301 (2014) Article DOI: 10.1016/j.bmcl.2014.06.001 BindingDB Entry DOI: 10.7270/Q2T43VRS
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Wistar rat small intestine sucrase after 30 mins				Bioorg Med Chem Lett 21: 738-41 (2011) Article DOI: 10.1016/j.bmcl.2010.11.112 BindingDB Entry DOI: 10.7270/Q2D21XVS
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal brush border membrane isomaltase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kindai University Curated by ChEMBL					Assay Description Inhibition of rat small intestinal isomaltase using isomaltose as substrate incubated for 30 mins by glucose-oxidase method				Bioorg Med Chem 24: 3705-15 (2016) Article DOI: 10.1016/j.bmc.2016.06.013 BindingDB Entry DOI: 10.7270/Q241700V
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal isomaltase using isomoltose as substrate				J Med Chem 55: 10347-62 (2012) Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 3298-301 (2014) Article DOI: 10.1016/j.bmcl.2014.06.001 BindingDB Entry DOI: 10.7270/Q2T43VRS
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |r| Show InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Wistar rat small intestine isomaltase after 30 mins				Bioorg Med Chem Lett 21: 738-41 (2011) Article DOI: 10.1016/j.bmcl.2010.11.112 BindingDB Entry DOI: 10.7270/Q2D21XVS
					More data for this Ligand-Target Pair