Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50124947 (CHEMBL453539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Inhibition of recombinant human matriptase catalytic domain pre-incubated for 60 mins before Boc QAR-AMC substrate addition | J Med Chem 62: 552-560 (2019) Article DOI: 10.1021/acs.jmedchem.8b01139 BindingDB Entry DOI: 10.7270/Q2MS3X3S | |||||||||||
More data for this Ligand-Target Pair |