Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Synaptic vesicular amine transporter' and Ligand = 'BDBM50172090'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50172090 ((4S)-2,4-bis(4-fluorobenzyl)-8-methyl-8-azabicyclo...) Show SMILES CN1C2CCC1C(Cc1ccc(F)cc1)=C[C@@H]2Cc1ccc(F)cc1 |c:16,TLB:7:6:1:4.3,THB:17:16:1:4.3| Show InChI InChI=1S/C22H23F2N/c1-25-21-10-11-22(25)18(13-16-4-8-20(24)9-5-16)14-17(21)12-15-2-6-19(23)7-3-15/h2-9,14,17,21-22H,10-13H2,1H3/t17-,21?,22?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-dihydrotetrabenazine binding to vesicular monoamine transporter-2 of rat synaptic vesicle membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50172090 ((4S)-2,4-bis(4-fluorobenzyl)-8-methyl-8-azabicyclo...) Show SMILES CN1C2CCC1C(Cc1ccc(F)cc1)=C[C@@H]2Cc1ccc(F)cc1 |c:16,TLB:7:6:1:4.3,THB:17:16:1:4.3| Show InChI InChI=1S/C22H23F2N/c1-25-21-10-11-22(25)18(13-16-4-8-20(24)9-5-16)14-17(21)12-15-2-6-19(23)7-3-15/h2-9,14,17,21-22H,10-13H2,1H3/t17-,21?,22?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-nicotine binding to vesicular monoamine transporter-2 of rat brain membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50172090 ((4S)-2,4-bis(4-fluorobenzyl)-8-methyl-8-azabicyclo...) Show SMILES CN1C2CCC1C(Cc1ccc(F)cc1)=C[C@@H]2Cc1ccc(F)cc1 |c:16,TLB:7:6:1:4.3,THB:17:16:1:4.3| Show InChI InChI=1S/C22H23F2N/c1-25-21-10-11-22(25)18(13-16-4-8-20(24)9-5-16)14-17(21)12-15-2-6-19(23)7-3-15/h2-9,14,17,21-22H,10-13H2,1H3/t17-,21?,22?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-methyllycaconitine binding to vesicular monoamine transporter-2 of rat brain membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair