Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM311398'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM311398 (US10155763, Example 6) Show SMILES Cc1cccc(n1)-c1nc2NCCn2c1-c1cc2cnccc2s1 Show InChI InChI=1S/C18H15N5S/c1-11-3-2-4-13(21-11)16-17(23-8-7-20-18(23)22-16)15-9-12-10-19-6-5-14(12)24-15/h2-6,9-10H,7-8H2,1H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of ALK5 (unknown origin)				Bioorg Med Chem Lett 29: 2070-2075 (2019) Article DOI: 10.1016/j.bmcl.2019.07.015 BindingDB Entry DOI: 10.7270/Q20868TQ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM311398 (US10155763, Example 6) Show SMILES Cc1cccc(n1)-c1nc2NCCn2c1-c1cc2cnccc2s1 Show InChI InChI=1S/C18H15N5S/c1-11-3-2-4-13(21-11)16-17(23-8-7-20-18(23)22-16)15-9-12-10-19-6-5-14(12)24-15/h2-6,9-10H,7-8H2,1H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
TIUMBIO CO., LTD. US Patent					Assay Description The kinase activity of ALK5 was assessed by measuring radiolabelled phosphate[33P] incorporation into the generic substrate, casein. The kinase domai...				US Patent US10155763 (2018) BindingDB Entry DOI: 10.7270/Q29C70HK
					More data for this Ligand-Target Pair