Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM406778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM406778 (3,5-difluoro-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,...) Show SMILES Cc1cccc(n1)-c1nc(Nc2c(F)cncc2F)c2cccn2n1 Show InChI InChI=1S/C17H12F2N6/c1-10-4-2-5-13(21-10)16-23-17(14-6-3-7-25(14)24-16)22-15-11(18)8-20-9-12(15)19/h2-9H,1H3,(H,20,22,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...				US Patent US10336761 (2019) BindingDB Entry DOI: 10.7270/Q2M90C2R
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM406778 (3,5-difluoro-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,...) Show SMILES Cc1cccc(n1)-c1nc(Nc2c(F)cncc2F)c2cccn2n1 Show InChI InChI=1S/C17H12F2N6/c1-10-4-2-5-13(21-10)16-23-17(14-6-3-7-25(14)24-16)22-15-11(18)8-20-9-12(15)19/h2-9H,1H3,(H,20,22,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assay				Bioorg Med Chem 26: 1026-1034 (2018) Article DOI: 10.1016/j.bmc.2018.01.014 BindingDB Entry DOI: 10.7270/Q27M0BHV
					More data for this Ligand-Target Pair