Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM406968'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM406968 ((3S)-1-({4-[(3-fluoropyridin-4-yl)amino]-2-(6-meth...) Show SMILES Cc1cccc(n1)-c1nc(Nc2ccncc2F)c2c(CN3CC[C@H](O)C3)ccn2n1 |r| Show InChI InChI=1S/C22H22FN7O/c1-14-3-2-4-19(25-14)21-27-22(26-18-5-8-24-11-17(18)23)20-15(6-10-30(20)28-21)12-29-9-7-16(31)13-29/h2-6,8,10-11,16,31H,7,9,12-13H2,1H3,(H,24,26,27,28)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...				US Patent US10336761 (2019) BindingDB Entry DOI: 10.7270/Q2M90C2R
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