Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM407012'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM407012 ((3-{[({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin-...) Show SMILES OCC1(CNCc2ccn3nc(nc(Nc4ccncc4F)c23)-c2ccccn2)COC1 Show InChI InChI=1S/C22H22FN7O2/c23-16-10-24-7-4-17(16)27-21-19-15(9-25-11-22(12-31)13-32-14-22)5-8-30(19)29-20(28-21)18-3-1-2-6-26-18/h1-8,10,25,31H,9,11-14H2,(H,24,27,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.25	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...				US Patent US10336761 (2019) BindingDB Entry DOI: 10.7270/Q2M90C2R
					More data for this Ligand-Target Pair