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Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50535756'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50535756
PNG
(CHEMBL4534375)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2C)nc1-c1ccc2nsnc2c1
Show InChI InChI=1S/C23H20N6S/c1-14-6-3-4-8-17(14)24-13-21-26-22(16-10-11-18-20(12-16)29-30-28-18)23(27-21)19-9-5-7-15(2)25-19/h3-12,24H,13H2,1-2H3,(H,26,27)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Yanbian University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...

Bioorg Med Chem Lett 29: 2070-2075 (2019)


Article DOI: 10.1016/j.bmcl.2019.07.015
BindingDB Entry DOI: 10.7270/Q20868TQ
More data for this
Ligand-Target Pair