Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1 [T204D]' and Ligand = 'BDBM282821'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 [T204D] (Homo sapiens (Human))	BDBM282821 ((R)-6-(4-(4-fluorophenyl)-1-(4,4,4-trifluoro-1- hy...) Show SMILES OC[C@@H](CC(F)(F)F)n1cnc(c1-c1ccc2ncc(C#N)n2n1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C20H14F4N6O/c21-13-3-1-12(2-4-13)18-19(29(11-27-18)14(10-31)7-20(22,23)24)16-5-6-17-26-9-15(8-25)30(17)28-16/h1-6,9,11,14,31H,7,10H2/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin at Madison					Assay Description Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...				J Med Chem 51: 7243-52 (2008) BindingDB Entry DOI: 10.7270/Q2B85BFB
					More data for this Ligand-Target Pair