Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-2' and Ligand = 'BDBM406802'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-2 (Homo sapiens (Human))	BDBM406802 (N-{2-[6-(trifluoromethyl)pyridin-2-yl]pyrrolo[2,1-...) Show SMILES FC(F)(F)c1cccc(n1)-c1nc(Nc2ccncc2)c2cccn2n1 Show InChI InChI=1S/C17H11F3N6/c18-17(19,20)14-5-1-3-12(23-14)15-24-16(13-4-2-10-26(13)25-15)22-11-6-8-21-9-7-11/h1-10H,(H,21,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...				US Patent US10336761 (2019) BindingDB Entry DOI: 10.7270/Q2M90C2R
					More data for this Ligand-Target Pair
TGF-beta receptor type-2 (Homo sapiens (Human))	BDBM406802 (N-{2-[6-(trifluoromethyl)pyridin-2-yl]pyrrolo[2,1-...) Show SMILES FC(F)(F)c1cccc(n1)-c1nc(Nc2ccncc2)c2cccn2n1 Show InChI InChI=1S/C17H11F3N6/c18-17(19,20)14-5-1-3-12(23-14)15-24-16(13-4-2-10-26(13)25-15)22-11-6-8-21-9-7-11/h1-10H,(H,21,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of wild type His-tagged TGFbetaR2 (unknown origin) after 1 hr by HTRF assay				Bioorg Med Chem 26: 1026-1034 (2018) Article DOI: 10.1016/j.bmc.2018.01.014 BindingDB Entry DOI: 10.7270/Q27M0BHV
					More data for this Ligand-Target Pair