Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TRAF2 and NCK-interacting protein kinase' and Ligand = 'BDBM173978'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM173978 (US9102637, 13) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(NCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H30N6O2S/c29-25(35)24-27(37-28(32-24)31-23-13-8-19-6-2-3-7-21(19)18-23)33-26(36)20-9-11-22(12-10-20)30-14-17-34-15-4-1-5-16-34/h2-3,6-13,18,30H,1,4-5,14-17H2,(H2,29,35)(H,31,32)(H,33,36)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair